Comprehensive Health and Aesthetic Botox Solutions with Rejenacell
At Rejenacell, our approach to Botox treatments goes beyond aesthetics; it also plays an important role in managing medical conditions such as muscle health, migraines, and excessive sweating. We apply Botox through personalized protocols tailored to each individual’s health needs and facial structure. Our goal is to provide patients with both medical relief and a natural, balanced aesthetic appearance. In this way, we deliver safe and effective results that enhance overall quality of life.
Assessment and treatment planning
Facial muscle contractions are evaluated, and the muscles responsible for the lines are identified.
Marking the treatment areas
Injection points are determined based on facial expressions.
Injections
Botox is administered in small amounts using fine needles. The procedure usually takes only 10–15 minutes and requires no recovery time.
Aftercare
Patients can resume normal activities the same day. However, heavy exercise, sauna, or facial massage are not recommended during the first 24 hours.
Key Advantages of Botox Application
Feel the Aesthetic Touch of Botox
Botox temporarily reduces excessive muscle contractions, resulting in smoother skin and a more relaxed, youthful appearance. Beyond its cosmetic benefits, it also stands out for its effectiveness in medical areas such as migraine, excessive sweating, and muscle spasms. At Rejenacell, we apply Botox through personalized protocols, aiming for safe and effective results while preserving the natural features of the face.
What is Botox?
How is Botox Applied?
What is Botox?
Today, Botox is one of the most commonly used procedures in modern medicine, sought not only for its cosmetic effects but also for many medical indications. Type A botulinum toxin is a purified protein derived from the bacterium Clostridium botulinum. Although the pure toxin is dangerous to the human body, medical treatments known as Botox injections are administered in minimal microgram doses.
The cosmetic use of Botox dates back to the 1980s. It was initially used to treat strabismus and eyelid spasms, and it was observed that wrinkles diminished when facial muscles relaxed. Today, hundreds of thousands of patients benefit from both cosmetic and therapeutic Botox treatments, allowing them to live their daily lives more comfortably.
Mechanism of Action of Botox
Botox works by blocking the release of a neurotransmitter (acetylcholine) at the neuromuscular junction. Commands for muscle contraction are transmitted through this chemical, acetylcholine. When Botox is injected, this communication is interrupted, the targeted muscle relaxes, and the contraction ceases. As a result:
The appearance of expression lines is reduced,
The skin surface becomes smoother,
The face reflects a more rested and relaxed look.
The effects of Botox typically last 3 to 6 months. After this period, nerve endings begin to release acetylcholine again, and muscle activity resumes. With repeated treatments, the strength of muscle contractions diminishes, keeping lines under control before they deepen. Therefore, Botox is regarded not only as a treatment but also as a preventive anti-aging approach.
Aesthetic Applications of Botox
For expression lines, Botox is considered the gold standard treatment in the facial area. It is especially effective for dynamic lines that appear even with repeated facial movements. The main areas of application are:
Forehead lines: Horizontal wrinkles that appear when raising the eyebrows.
Glabellar lines (between the eyebrows): Vertical lines that give an angry or tired expression.
Crow’s feet: Fine lines that develop around the eyes when smiling.
Bunny lines: Fine lines that appear on the bridge of the nose when smiling.
Vertical lines on the upper lip: Often referred to as “barcode” lines, more prominent in smokers.
Neck lines and platysma bands: Vertical neck lines that form as neck muscles weaken over time.
Bruxism (teeth grinding) and jawline: Injections into the overactive masseter muscles caused by bruxism help them relax, giving the face a more oval shape.
Eyebrow lift (Botox lift): Slightly lifting the eyebrows to create a younger, more vibrant expression.
Medical Applications of Botox
Botox is important not only for aesthetic purposes but also for medical use. It is especially preferred in neuromuscular system disorders and conditions related to excessive sweating.
Excessive sweating (hyperhidrosis): Botox is used to treat overactive sweat glands in the armpits, palms, and soles of the feet. The desired effect usually lasts from 6–9 months up to 12 months.
Migraine prevention: An FDA-approved treatment that reduces the frequency and severity of chronic migraine attacks. Injections in the head and neck area provide significant relief from headaches.
Muscle spasms: Beneficial for conditions such as eyelid twitching and cervical dystonia, where muscles contract involuntarily.
Spasticity: Helps reduce muscle spasms in patients with stroke or cerebral palsy.
Bruxism and temporomandibular joint disorders: Reduces jaw pain and muscle hypertrophy associated with nighttime teeth grinding.
How is Botox Applied?
Botox injection is an affordable and temporary procedure. The application process is as follows:
Assessment and treatment planning: Facial muscle contractions are evaluated, and the muscles responsible for the lines are identified.
Marking the treatment areas: Injection points are determined based on facial expressions.
Injections: Botox is applied in small amounts using fine needles. The procedure usually takes only 10–15 minutes and requires no recovery time.
Aftercare: Patients can resume their normal daily activities on the same day. However, heavy exercise, sauna, or massage is not recommended during the first 24 hours.
Expected Effects After Botox
Effects are noticeable within 2 to 4 days,
Peak effect occurs within 10 to 14 days,
Results last on average 4 to 6 months.
For individuals receiving Botox for the first time, the effect may be slightly shorter. With regular treatments and repeated muscle relaxation, more lasting and long-term results can be achieved.
Possible Side Effects and Complications of Botox
When administered by trained professionals, Botox is a safe procedure. However, like all medications, it may have some side effects:
Mild redness, swelling, or bruising,
Localized reactions at the injection site,
Rarely, eyelid drooping (ptosis),
Temporary facial asymmetry.
These side effects are usually temporary and disappear within a few weeks.
Everything You Want to Know
About Botox
Situations to Avoid Botox
Not every patient is suitable for Botox. Contraindications are defined as follows:
Pregnant and breastfeeding women
Neurological and muscular disorders (e.g., myasthenia gravis)
Acute infection at the injection site
History of allergy to botulinum toxin
Current Literature and Clinical Experiences
Recent clinical studies have shown that Botox is not only cosmetic but also improves patients’ quality of life. The FDA’s approval of Botox for migraine treatment is the best evidence of this. It has also been reported that Botox provides one of the highest treatment success rates for excessive sweating, significantly improving the social and professional lives of those affected.
For aesthetic purposes, Botox is increasingly used either alone or in combination therapies (such as hyaluronic acid fillers, mesotherapy, or PRP). These combinations accelerate skin rejuvenation and provide more natural results.
Advantages of Botox
A non-surgical procedure
Very short application time, usually no more than 10–15 minutes
Minimal discomfort, no anesthesia required
Immediate return to daily activities
With continuous use, it functions as a preventive anti-aging treatment
When does the effect start, and when should it be assessed?
Onset: Usually appears within 3–4 days.
Peak effect: Day 10–14 (the best time for evaluation).
Duration: On average 3–6 months, depending on muscle strength, dosage, individual metabolism, and indication.
Follow-up examination and touch-up (completion) strategy
Check-up time: Day 10–14 (optimal time). Too early (e.g., days 3–5) may give misleading results.
Touch-up indications: Significant asymmetry, insufficient inhibition of the target muscle, or persistent dynamic wrinkles in a localized area.
Frequently Asked / Misunderstood
Air travel: Pressure differences do not affect Botox; it is safe. Avoid tight eye masks/hats that put pressure on the treated area within the first 24 hours.
“Does drinking a lot of water spread the toxin?” No; hydration is good for skin and recovery but does not affect the activity of the toxin.
“Do you use hot compresses to reduce swelling?” Cold packs are more effective within the first 48–72 hours; heat may worsen the condition.
“Does massage make it work faster?” Not necessarily; it can increase the risk of diffusion and asymmetry.
When to Consult a Doctor
Severe headache, vision problems, persistent significant bruising/swelling, fever, marked muscle weakness, or difficulty swallowing/speaking.
If you experience eyelid drooping or ongoing muscle weakness that does not resolve, do not wait until your next scheduled injection.
Conclusion
Botox is a well-established treatment for both aesthetic and medical purposes. It not only minimizes wrinkles—providing patients with a younger and healthier appearance—but also improves quality of life in medical conditions such as migraines and excessive sweating. The success of the treatment is closely linked to the physician’s knowledge of muscle anatomy and precise dosage application. Therefore, Botox should only be performed by skilled doctors. When used correctly, Botox remains one of the best and most reliable methods modern medicine has to turn back the clock on aging.
Post-Botox Patient Care
The following is a brief “aftercare protocol” commonly used in clinical practice to ensure safe recovery and maximum effectiveness after facial aesthetics (forehead–glabella–crow’s feet–bunny lines–upper lip–platysma) and medical treatments (hyperhidrosis, migraine, masseter, bruxism, etc.). Timelines are approximate—always follow your doctor’s instructions.
First Hours (0–6 hours)
Head and neck posture: Remain upright for the first 3–4 hours. Avoid lying down for long periods or keeping your head bent forward.
Touching/massaging injection sites: Avoid rubbing, massaging, or applying pressure to the treated areas.
Facial movements/activation: Some clinicians recommend light facial movements (e.g., gently activating forehead or crow’s feet muscles for 10–15 minutes), but avoid exaggerated expressions or intense facial exercises.
Makeup: Wait at least 6 hours; when applying, do not press or rub harshly with brushes.
Water, Heat, and Environment (24–72 hours)
Shower: Take lukewarm showers in the first 24 hours; avoid hot water or prolonged steam exposure. Do not apply hot water forcefully to the skin.
Heat sources: Avoid sauna, steam bath, hot yoga, steam rooms, or tanning beds for 48–72 hours (heat increases vasodilation and risk of product spread).
Sun: Do not sit in direct sun for 24–48 hours. If necessary, protect with a wide-brimmed hat and mineral sunscreen (apply gently, without pressing).
Ice: If bruising/swelling occurs, apply cold packs to the area during the first 6–12 hours; avoid direct skin contact with ice.
Exercise and Physical Activity
High-intensity exercise (HIIT, running, CrossFit, heavy weights): Avoid for 24–48 hours (increased blood flow and heat raise risk of bruising/spread).
Light activity: A gentle walk is fine after 4–6 hours.
Facial/oral movements: Avoid face yoga, chewing gum, heavy whistling, or strong breathing exercises for 24–48 hours (especially for lip and masseter areas).
Diet, Alcohol, and Hydration
Alcohol: Avoid 24 hours before and 24–48 hours after treatment (vasodilation → higher risk of bruising/swelling).
Hydration: Drink adequate water throughout the day (helps balance swelling and supports skin recovery).
Salty, spicy, or very hot foods: Limit for the first 24 hours (may worsen flushing or swelling).
Supplements/herbal products: Pause supplements known to increase bruising, e.g., Omega-3, Ginkgo, garlic extract, high-dose vitamin E, curcumin (typically avoided for 24–48 hours unless your doctor advises otherwise).
Caffeine: Optional, but reducing intake 1–2 days before may help with swelling/flushing.
Medications and Skincare Products
NSAIDs (ibuprofen, naproxen, aspirin): Avoid for 24 hours if possible (they increase bruising risk).
Retinoids/acid peels/exfoliants: Avoid for 24–48 hours; use gentle cleansers and barrier-friendly moisturizers instead.
Topical steroids/antibiotics: Only as directed by your physician; routine preventive use is not required.
If eyelid drooping occurs (rare): Your doctor may prescribe temporary eye drops such as apraclonidine or brimonidine (requires consultation).
Sleep, Pressure, and Accessories
Sleep position: On the first night, sleep on your back with 1–2 pillows to slightly elevate your head.
Avoid pressure: For the first 24 hours, avoid anything tight against the treated area, such as narrow-framed glasses pressing on the nose bridge, hats, beanies, headbands, or face-compressing sleep masks.
Massage/rollers/guasha: Avoid for at least 7 days (especially on forehead, glabella, and periorbital areas).
Other Procedures and Appointments
Facials/massage/microdermabrasion/RF/HIFU/microneedling: Wait 7–14 days.
Laser/chemical peels: Schedule at least 7–14 days after the treatment.
Dental procedures/cleanings: If upper lip/jaw was treated, wait 3–7 days (to avoid excess muscle strain).
Vaccinations/blood draws: Minimize injections near facial muscles on the same day; consult your doctor for scheduling other injectable treatments.
Special Notes by Area
Masseter (bruxism/facial slimming): Avoid hard gum, tough meats, or difficult-to-chew foods for 24–48 hours.
Axillary hyperhidrosis: Avoid shaving and alcohol-based deodorants for 24 hours, and avoid intense workouts/heat exposure for 48 hours.
Neck/platysma: Avoid overextending your head backward or lifting your chin up. No heavy neck exercises or tight scarves for 24–48 hours.
Our Personalized
Botox Treatment
Targeted Effect
Botox is applied only to the relevant muscles, softening lines while preserving natural facial features.
Scientific and Safe
Performed by specialists, following scientific protocols and safe dosing.
Natural Results
The goal is not a frozen look, but a refreshed and relaxed appearance.
Quick and Comfortable
A short procedure with no downtime, allowing you to return to daily life immediately.